The BioCyc web portal from SRI International contains genome and metabolic-pathway information for over 14,000 microbes. The BioCyc website provides a suite of software tools for database searching and visualization, for omics data analysis, and for comparative genomics and comparative pathway questions.
Key aspects of BioCyc data:
Quality data curated from tens of thousands of publications, including curated databases for E. coli, B. subtilis, H. sapiens, and S. cerevisiae.
Computationally predicted metabolic pathways and operons.
Data integrated from other databases including gene essentiality, regulatory networks, protein features, and GO annotations.
http://www.phoenixbioinformatics.org/biocyc#product-biocyc-about